In the sweetRNA project, we aim to develop innovative RNA-based biopesticides that act specifically and effectively against the cixiidae Pentastiridius leporinus and the pathogens it transmits. This cicada poses an increasing threat to sugar beet cultivation in Germany, as it transmits bacteria that cause low sugar content syndrome (SBR), which leads to significant crop losses. As conventional control methods such as neonicotinoids are no longer permitted, new control measures are urgently needed. 

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The project covers two main areas: the development and testing of RNA active ingredients and research into the basic mechanisms of RNA uptake and stability and the interaction of the pathogens with the host plants. A particular focus is on the development of phloem-mediated RNA formulations, which represent an innovation in RNA-based plant protection. The integration of different RNA species, such as dsRNA and antisense circRNAs, forms the basis for targeted and effective plant protection solutions against Pentastiridius leporinus and the pathogens in transmits.