Our research focusses on non-coding RNAs and the molecular mechanisms that regulate them, including gene expression, DNA and histone modifications, and targeted mRNA degradation. Building on this fundamental knowledge, we have pioneered RNA spray-based technologies that control cellular RNA-dependent processes. A particular focus is on RNAi (RNA interference), which enables the sustainable enhancement of crop stress resistance. This pioneering approach has received international recognition (RNA spray fights fungus), and demonstrates the potential of RNA sprays to transform crop protection. We are also exploring other RNA species, including circRNAs, mRNAs, and CRISP/Cas RNAs, for use as sprayable RNA in crops and research extending the scope of this innovative technology. Working at the interface of basic and applied research, we investigate how RNA molecules are taken up, transported, and processes by plant cells, as well as their stability, efficacy, and environmental behavior. This knowledge allow us to translate molecular insights into practical solutions, creating innovative tools for efficient and sustainable agriculture whole advancing RNA-based technologies.