RNA-based innovations: phytomedicine meets RNA biology
Our research focusses on non-coding and coding RNAs and the molecular mechanisms that control them. This includes the regulation of gene expression, DNA and histone modifications, and the targeted degradation of mRNAs.
Based on this knowledge, we develop interdisciplinary RNA spray-based technologies that specifically control cellular RNA-dependent processes. A particular focus is on the non-gene editing application of RNAi-dsRNAs. This innovative spray technology makes it possible to increase the stress resistance of crops in a sustainable and environmentally friendly way - an approach that is attracting international attention (e.g. 'RNA spray fights fungus', Nature).
Furthermore, we are also developing other RNA species, including circRNAs, mRNAs and CRISPR/Cas RNAs, for use as sprayable RNA in crop production and research.
Our focus: Understanding and applying the molecular principles
We investigate how RNA molecules are taken up, transported and processed by plant cells as well as their stability, efficacy and environmental behavior. This knowledge forms the basis for our interdisciplinary projects, which aim to translate scientific findings into practical solutions. With these approaches, we create innovative tools for efficient and sustainable agriculture and at the same time drive the development of new technologies.
Find out more about our projects and developments here.