RNA interference (RNAi) is a conserved mechanism in eukaryotes that allows the development of a ground-breaking technology which enables precise and environmentally friendly control of pests and pathogens. Compared to conventional plant protection products, products using RNAi offer decisive advantages: they are highly specific, protect beneficial organisms such as pollinators and have less of an impact on the environment. The effectiveness of the method against many agriculturally relevant pests has been scientifically proven. The first RNAi products, such as the biopesticide Calantha, have already been authorized in the USA and further developments are about to be launched on the market.

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RNAi utilizes a natural mechanism of gene regulation. This involves targeted silencing of genes through double-stranded RNA (dsRNA). When this RNA is sprayed onto plants, it enters the pest's cells via the digestive system. There it stops the production of vital proteins and thus effectively combats the pests - without altering the genetic material of the plant or pest.

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Find out more in the video: How RNAi-based plant protection works.

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One of the biggest challenges when using RNAi plant protection products is the stability and transport of the RNA. Nucleases that degrade RNA can impair efficacy. Our research focuses on the development of stable RNA formulations that enable effective and sustainable application. We work closely with universities, research institutes and industry partners to develop innovative solutions.

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Here you can find more information about our projects and development.