To successfully implement RNA-based applications in agriculture, an in-depth understanding of the mechanisms underlying the uptake of exogenous RNAs in plants is crucial. Our research aims to identify the factors that enable or prevent the uptake and transport of RNAs in crop plants. This knowledge forms the basis for the targeted optimization of RNA sprays for different plant species and pathosystems. 

​

In co-operation with leading research institutes, we are investigating the differences between plant species that respond to RNA sprays and those that do not. We analyze characteristics such as stomatal density, -architecure and -distribution using modern imaging techniques. At the same time, we are testing the stability and degradation properties of RNAs in apoplastic fluid and developing new formulation approaches in collaboration with chemists. 

​

In addition, we are investigating pathogen-specific uptake mechanisms, particularly in neurotrophic fungi such as *Fusarium graminearum*. So far our results show that these fungi are able to efficiently take up unprocessed dsRNAs and degrade target transcripts via their RNAi machinery. These findings will help to optimize RNA sprays specifically for pathogens and increase their efficiency. 

​

​