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BASIC SCIENCE
RNA Stability

The stability of exogenous RNAs is a key criteria for their systemic distribution and efficacy in plants. Using a combination of molecular, biochemical and imaging approaches, we have shown that exogenous RNAs are transported into barley via the phloem and xylem. Using stylectomy and sequencing techniques, we identify factors that influence the stability of RNAs during dispersal. 

Another focus is the analysis of processing patterns of dsRNA by plant Dicer proteins. This enables the design of specific and stable RNA sequences for biopesticides. We are also investigating RNA-binding proteins that could increase the stability of RNAs in order to improve the duration of action and range of RNA sprays. Our research results are directly incorporated into the development of innovative strategies for the efficient and sustainable use of exogenous RNAs in practice. 

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