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PUBLICATIONS

  1. Vural Uslu, V., Dalakouras, A. Sueselbeck, L., & Koch, A. (2026). RNA meets agriculture: From molecular mechanisms to market applications. Annual Review of Plan Biology, 77, X-X

  2. Vural Uslu, V., Dobrowitsch, M., Preussel Danger, K., Furch, A. U., Noetzold, J., Richter, A. M., Schlemmer, T., Dong, Y., Krczal, G., & Koch, A. (2025). Foliar mRNA spray induces protein synthesis in monocot crop and dicot model plant species. bioRxiv.

  3. Ilic, A. - M.,  Witczak, N., Maixner, M., Koch, A., Dunemann, S., Huettel, B., & Kube, M. (2026). Comparative genome analysis of 16SrXII-A ´Candidatus Phyoplasma solani´ POT transmitted by Hyalesthes obsoletus. Microorganisms, 14, 226

  4. Palatinus, L.R., Schlemmer, T., & Koch, A. (2025). Technical advances in extracellular vesicle isolation from fungi and oomycetes: Insights from plant-pathogenic species. Fungal Biology Reviews, 53, 100444.

  5. Alkemade, J.A., Hawkins, N. J. Baraldi, E., Buddie, A. G., Cockerton, H. M., Corkley, I., Fraaije, B.A., Gaya, E., Gifford, D. R., Hartig, F., Koch, A., et al. (2025). Learning from fungicide resistance: Evolutionary insights to guide RNAi--based control of fungal crop pathogens. Fungal Biology Reviews, 53, 100443

  6. Arroyo Villora, S., Zhao, Y., Castellanos Silva, P., et al. (2025). Epigenetic silencing and CRISPR-mediated reactivation of tight junction protein claudin10b (CLDN10B) in renal cancer. Clinical Epigenetics, 17, 102.

  7. Furch, A.C.U., Zimmermann, M.R., Noll, G.A., Wrobel, L.S., Scholz, S.S., Buxa-Kleeberg, S.V., Hafke, J.B., Fliegmann, J., Mithöfer, A., Ehlers, K., Haufschild, T., Nötzold, J., Koch, A.M., Grabe, V., Teutemacher, F., Maaß, J.-P., Prüfer, D., Oelmüller, R., Peiter, E., Kogel, K.-H., & van Bel, A.J.E. (2025). Transformation of flg22 perception into electrical signals decoded in the vasculature leads to sieve tube blockage and pathogen resistance. Science Advances (in press).

  8. Koch A. (2025) RNAi – neue Lösungsansätze für die Bekämpfung tierischer Schaderreger im Mais“, Fachzeitschrift „mais“, DLG-Verlag, Ausgabe 01/2025

  9. Koch A. (2025) Alternative Wege im Pflanzenschutz: RNAi-basierte Mittel und der Stand der Forschung“, Die Zuckerrübenzeitung (dzz) (in press).

  10.  Amineni V.P.S., Petschenka G., Koch A. (2024) Double-stranded DNA reduces dsRNA degradation in the saliva and significantly enhances RNAi-mediated gene silencing in Halyomorpha halys. Advanced Biology, under revision. bioRxiv. https://doi.org/10.1101/2024.10.10.617619;

  11. Hinrichs AK, Koch A, Richter A (2024) Dual-Luciferase Reporter Assay for Prescreening CRISPR (d)Cas9-Mediated Epigenetic Editing on a Plant Promoter Using Human Cells. Methods in Molecular Biology 2787, Plant Functional Genomics. DOI : 10.1007/978-1-0716-3782-1 

  12. Arroyo Villora, S., Zhao, Y., Castellanos Silva, P., Olanin, V., Groll, D., Maurer, S., Roetzer, V., Szymanski, W., Procida-Kowalski, T., Philipp, N., Koch, A., Bartkuhn, M., Graumann, J., Volckmann, R., Koster, J., Rossbach, O., Salzig, D., Dammann, R., Sigges, C., Halbritter, J., Haerteis, S., & Richter, A. M. (2024). Epigenetic silencing and CRISPR-mediated reactivation of tight junction protein Claudin10B (*CLDN10B*) in renal cancer. Clinical Epigenetics, under revision.

  13. Chen A, Halilovic L, Shay JH, Koch A, Mitter N and Jin H. (2023). Improving RNA-based crop protection through nanotechnology and insights from cross-kingdom RNA trafficking. Curr. Opin. Plant Biol. 76, 102441.

  14. Kümin M, Eyer K, Hall J, Koch A, Pascolo S, Romeis J (2024) RNA-Technologien: Wirkmechanismen, Anwendungen und Verabreichungsformen. Swiss Academies Reports 19 (1)

  15. Koch, A (2024) Zukunft im Pflanzenschutz: Ersetzen RNA-Sprays bald chemische Mittel? Agrarheute. Verfügbar unter: https://www.agrarheute.com/pflanze/kartoffeln/zukunft-pflanzenschutz-ersetzen-rna-sprays-bald-chemische-mittel-620889

  16. Koch A. (2024) Potenziale und Herausforderungen des RNA-basierten Pflanzenschutzes, Der Pflanzenarzt, Österreichischer Agrarverlag.

  17. Koch A. (2024) Pro&Contra RNAi-Spray, Ökologie & Landbau.

  18. Koch, A. (2024). RNA-based crop protection: potential, challenges, and practical examples. Journal of Consumer Protection and Food Safety, 19, 127–129.

  19. Koch A (2023) Development of RNAi-based biopesticides, regulatory constraints, and commercial prospects. In: Koul O (editor). Development and Commercialization of Biopesticides: Costs and Benefits. Academic Press; 2023. pp. 149–171. doi: 10.1016/B978-0-323-95290-3.00013-3

  20. Koch A. (2023) So wirkt die RNA-Schluckimpfung gegen Schadwanzen“, Fruchthandelmagazin 32-33.

  21. Koch A. (2023) RNA-Wirkstoffe gegen den Kartoffelkäfer sind vielversprechend“, Kartoffelbau 4/2023 (74. Jg.).

  22. Schlemmer T, Lischka R, Biedenkopf D, Koch A (2022) Extracellular vesicles isolated from dsRNA sprayed barley plants exhibit no growth inhibition or gene silencing in Fusarium graminearum. Fungal Biology and Biotechnology, 9, 1–14

  23. Koch A. & Petschenka G. (2022). Exogenous application of RNA for environmentally friendly control of insect pests. Journal of Cultivated Plants 74, 75–84. doi:10.5073/JfK.2022.03-04.05.

  24. Galli M, Martiny E, Imani J, Kumar N, Koch A, Steinbrenner J, Kogel K-H (2022) CRISPR/SpCas9-mediated double knockout of barley Microrchidia MORC1 and MORC6a reveals their strong involvement in plant immunity, transcriptional gene silencing and plant growth. Plant Biotechnology Journal doi:https://doi.org/10.1111/pbi.13697.

  25. Koch A and Wassenegger M (2021) - Tansley insight on the topic of ‘Host-induced gene silencing - mechanisms and applications’. New Phytologist 231: 54-59. https://doi.org/10.1111/nph.1736

  26. Schlemmer T, Barth P, Höfle L, Preußer C, Hardt M, Möbus A, Jelonek L, Busche T, Koch A (2021) Isolation and characterization of barley (Hordeum vulgare) extracellular vesicles to assess their role in RNA spray-based crop protection. Int. J. Mol. Sci. 22, 7212. https://doi.org/10.3390/ijms22137212

  27. Werner BT, Koch A, Šečić E, Engelhardt J, Jelonek L, Steinbrenner J, Kogel KH (2021) Fusarium graminearum DICER-like-dependent sRNAs are required for the repression of host immune genes and full virulence. Plos One https://doi.org/10.1371/journal.pone.0252365.

  28. Rank AP and Koch A (2021) Lab to Field Transition of RNA Spray Applications – How Far Are We? Front. Plant Sci. 12, 2243. https://www.frontiersin.org/article/10.3389/fpls.2021.755203. 

  29. Schlemmer T, Höfle L, Werner BT, Biedenkopf D, Preusser C, Hardt M, Möbus A, Claar M, Jelonek L, Goesmann A, Garikapati V, Spengler B, Perlet C, Busche T, Kalinowski J, Koch A (2021) Host-induced gene silencing involves transfer of dsRNA-derived siRNA via extracellular vesicles. BioRxiv. https://doi.org/10.1101/2020.02.12.945154

  30. Schlemmer T, Lischka R, Koch A (2020) Elucidating the role of extracellular vesicles in the Barley-Fusarium interaction. Trillium Extracellular Vesicles https://doi.org/10.47184/tev.2020.01.03

  31. Biedenkopf D, Will T, Knauer T, Jelonek L, Furch ACU, Busche T, Koch A (2020) Systemic spreading of exogenous applied RNA biopesticides in the crop plant Hordeum vulgare. exRNA https://doi.org/10.1186/s41544-020-00052-3

  32. Werner BT, Gaffar FY, Schuemann J, Biedenkopf D, Koch A (2020) RNA-spray-mediated silencing of Fusarium graminearum AGO and DCL genes improve barley disease resistance. Frontiers in Plant Science doi: 10.3389/fpls.2020.00476. 

  33. Koch A, Höfle L, Jelonek L, Busche T, Möbus A, Hardt M, Short distance spreading of non-coding RNAs: Vesicle trafficking and exosome secretion. In: Deising HB; Fraaije B; Mehl A; Oerke EC; Sierotzki H; Stammler G (Eds), "Modern Fungicides and Antifungal Compounds", Vol. IX, pp. 249-254. © 2020. Deutsche Phytomedizinische Gesellschaft, Braunschweig, ISBN: 978-3-941261-16

  34. Höfle L, Shrestha A, Werner BT, Jelonek L, Koch A (2019) Study on the efficacy of dsRNAs with increasing length targeting Fusarium graminearum CYP51 genes comparing HIGS and SIGS approaches. RNA Biology doi: 10.1080/15476286.2019.1700033 

  35. Koch A*, Höfle L*, Werner BT, Imani J, Schmidt A, Jelonek L, Kogel K-H (2019) SIGS vs HIGS: A study on the efficacy of two dsRNA delivery strategies to silence Fusarium FgCYP51 genes in infected host and non-host plants. Molecular Plant Pathology doi: 10.1111/mpp.12866 

  36. Gaffar FY and Koch A (2019) Catch me if you can! RNA silencing-based improvement of antiviral plant immunity. Viruses doi: 10.3390/v11070673. 

  37. Höfle L, Shrestha A, Werner BT, Jelonek L, Koch A (2019) Study on the efficacy of dsRNAs with increasing length targeting Fusarium graminearum CYP51 genes comparing HIGS and SIGS approaches. RNA Biology doi: 10.1080/15476286.2019.1700033 

  38. Koch A*, Höfle L*, Werner BT, Imani J, Schmidt A, Jelonek L, Kogel K-H (2019) SIGS vs HIGS: A study on the efficacy of two dsRNA delivery strategies to silence Fusarium FgCYP51 genes in infected host and non-host plants. Molecular Plant Pathology doi: 10.1111/mpp.12866 

  39. Gaffar FY and Koch A (2019) Catch me if you can! RNA silencing-based improvement of antiviral plant immunity. Viruses doi: 10.3390/v11070673. 

  40. Gaffar FY, Imani J, Karlovsky JP, Koch A and Kogel KH (2018) Various components of the RNAi pathway are required for conidiation, ascosporogenesis, virulence, DON production and SIGS-mediated fungal inhibition by exogenous dsRNA in the Head Blight pathogen Fusarium graminearum. Frontiers in Microbiology, doi.org/10.3389/fmicb.2019.01662 

  41. Klessig DF, Manohar M, Baby S, Koch A, Danquah WB, Luna E, Park H-J, Turgeon BG, Nelson R, Leach JE, Williamson VM, Kogel K-H, Kachroo A, Schroeder FC (2018) Nematode ascaroside enhances resistance in a broad spectrum of plant-pathogen systems. Phytopathology doi.org/10.1111/jph.12795. 

  42. Koch A, Stein E, Kogel KH (2018) RNA-Based Disease Control as a Complementary Measure to Fight Fusarium Fungi Through Silencing of the Azole Target Cytochrome P450 Lanosterol C-14 α-Demethylase. European Journal of Plant Pathology doi.org/10.1007/s10658-018-1518-4. 

  43. Koch A, Kang HG, Steinbrenner J, Dempsey DA, Klessig DF and Kogel KH (2017) MORC Proteins: Novel Players in Plant and Animal Health. Frontiers in Plant Science doi.org/10.3389/fpls.2017.01720. 

  44. Koch A, Kogel KH (2017) RNA-based Control of Plant Diseases: A Case Study with Fusarium graminearum. In: Plant Gene Silencing: Mechanisms and Applications; Tamas Dalmay (ed). 5. CABI Biotechnology Series, ISBN 9781780647678. 

  45. Koch A et al., An RNAi-based Control of Fusarium graminearum Infections Through Spraying of Long dsRNAs. In: Deising HB; Fraaije B; Mehl A; Oerke EC; Sierotzki H; Stammler G (Eds), "Modern Fungicides and Antifungal Compounds", Vol. VIII, pp. 63-66. © 2017 Deutsche Phytomedizinische Gesellschaft, Braunschweig, ISBN: 978-3-941261-15-0. 

  46. Kogel KH, Kumar N, Imani J, Koch A (2017) The agronomic potential of gene silencing applications. In: Deising HB; Fraaije B; Mehl A; Oerke EC; Sierotzki H; Stammler G (Eds), "Modern Fungicides and Antifungal Compounds", Vol. VIII, pp. 25-32 2017 © 2017 Deutsche Phytomedizinische Gesellschaft, Braunschweig, ISBN: 978-3-941261-15-0

  47. Koch A, Biedenkopf B, Furch ACU, Abdellatef E, Weber L, Linicus L, Johannsmeier J, Jelonek L, Goesmann A, Cardoza V, McMillan J, Mentzel T, Kogel KH (2016) An RNAi-based control of Fusarium graminearum infections through spraying of long dsRNAs involves a plant passage and is controlled by the fungal silencing machinery Plos Pathogens doi: 10.1371/journal.ppat.1005901.

  48. Abdellatef E, Will T, Koch A, Imani J, Vilcinskas A, Kogel KH (2015) Silencing the expression of the salivary sheath protein causes transgenerational feeding suppression in the aphid Sitobion avenae. Plant Biotechnology Journal doi: 10.1111/pbi.12322. 

  49. Manosalva P, Manohar M, von Reuss SH, Chen S, Koch A, Kaplan F, Choe A, Micikas RJ, Wang X, Kogel KH, Sternberg PW, Williamson VM, Schroeder FC, Klessig DF (2015) Conserved nematode signalling molecules elicit plant defenses and pathogen resistance. Nature Communications doi: 10.1038/ncomms8795. 

  50. Koch A, Kogel KH (2014) New wind in the sails: improving the agronomic value of crop plants through RNAi-mediated gene silencing. Plant Biotechnology Journal doi: 10.1111/pbi.12226. 

  51. Langen G, von Einem S, Koch A, Imani J, Pai S, Manohar M, Ehlers K, Choi HW, Claar M, Schmidt R, Mang HG, Bordiya Y, Kang HG, Klessig DF, Kogel KH (2014) The CRT1 subfamily of Microrchidia ATPases Regulates 1 Disease Resistance in Barley to Biotrophic and Necrotrophic Pathogens. Plant Physiology doi:10.1104/pp.113.227488. 

  52. Pöppel AK, Koch A, Kogel KH, Vogel H, Kollewe C, Wiesner J, Vilcinskas A (2014) Lucimycin, an antifungal peptide from the therapeutic maggot of the common green bottle fly Lucilia sericata. Biological Chemistry doi: 10.1515/hsz-2013-0263. 

  53. Koch A., Kogel KH. (2014) RNAi-mediated Gene Silencing and Its Implications for Agriculture, ISB News Report, Virginia Polytechnic Institute and State University, November.

  54. Koch A., Kogel KH. (2014) Neue RNAi-basierte Techniken – ein Paradigmenwechsel im Pflanzenschutz“, Mühle & Mischfutter, 151, Heft 14, Dezember.

  55. Koch A, Kumar N, Weber L, Keller H, Imani J and Kogel KH (2013) Host-induced gene silencing of cytochrome P450 lanosterol C14α-demethylase-encoding genes confers strong resistance to Fusarium spec. PNAS, doi: 10.1073/pnas.1306373110. 

  56. Koch A, Khalifa W, Langen G, Vilcinskas A, Kogel KH and Imani J (2012) The antimicrobial peptide thanatin reduces fungal infections in Arabidopsis. Journal of Phytopathology doi: 10.1111/j.1439-0434.2012.01946.x.

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